ʻO ka Polyvinyl Alcohol (PVA) Papa Lāʻau Lapaʻau no ka Uhi ʻana i nā Papa | Mea Hana Kiʻiʻoniʻoni Maʻemaʻe Kiʻekiʻe, Kūpono GMP, Kāinoa ʻia ʻo CDE

ʻO kā mākou Pharmaceutical Grade Polyvinyl Alcohol (PVA) he polymer synthetic maʻemaʻe kiʻekiʻe, hoʻoheheʻe ʻia i ka wai i hoʻohana nui ʻia ma ke ʻano he excipient lāʻau lapaʻau. Kūlike ia me nā pharmacopoeias nui e like me USP-NF, EP, JP, a me ChP, me ka hoʻopaʻa inoa CDE (F20209990114). Hana ʻo PVA ma ke ʻano he mea hana kiʻiʻoniʻoni maikaʻi loa no ka uhi ʻana i nā papa, ka mea hoʻopaʻa no ka granulation pulu, ka mea hoʻomānoanoa no nā hopena ophthalmic, a me ka emulsifier/stabilizer i nā ʻano hana like ʻole. Hāʻawi ia i nā waiwai pale makū kiʻekiʻe, ka ikaika hoʻopili kiʻekiʻe, a me ke kūpaʻa kemika maikaʻi loa. Loaʻa i ka papa hydrolyzed hapa (85-89 mol%) me ka viscosity i kāohi ʻia (4.6-6.0 mPa·s no ka hopena 4%)Hana ʻia ma lalo o nā hale hana GMP-compliant, kūpono no nā noi lāʻau lapaʻau waha, topical, a me ka ophthalmic.

Kāhea iā mā˚ou

Nā kikoʻī huahana

ʻO ka Polyvinyl Alcohol (PVA) Papa Lāʻau Lapaʻau

ʻIke Huahana

ʻO ka Polyvinyl Alcohol (PVA) kahi polymer synthetic wai-soluble i ʻike nui ʻia he excipient versatile a koʻikoʻi hoʻi i ka ʻoihana lāʻau lapaʻau.Hana ʻia kā mākou PVA lāʻau lapaʻau ma lalo o nā kulekele GMP paʻa, e hōʻoiaʻiʻo ana i ka maʻemaʻe kiʻekiʻe, ka maikaʻi kūlike, a me ka hoʻokō piha ʻana me nā kūlana pharmacopoeia honua.

ʻIke Huahana:

Inoa Kemika:ʻAlakō Polyvinyl
Helu CAS:9002-89-5
Helu Hoʻopaʻa Inoa CDE:F20209990114
Hoʻokō ʻana i ka Pharmacopoeia:ChP, USP-NF, EP, JP
Papa:Hoʻokahe hapa ʻia (85-89 mol%)
Ka mānoanoa (4% hopena, 20°C):4.6-6.0 mPa·s

Nā Hiʻohiʻona Koʻikoʻi a me nā Pōmaikaʻi

1. Nā Waiwai Hana Kiʻiʻoniʻoni Maikaʻi Loa

Hoʻokumu i nā ʻili ʻili mānoanoa, ikaika, a palupalu hoʻi kūpono no ka uhi ʻana i nā papa
Hāʻawi i ka pale ʻana i ka makū a me ka oxygen, e hoʻonui ana i ka paʻa o ka huahana a me ke ola papa
Ka hiki ke uhi ʻala maikaʻi

2. Ikaika Hoʻopaʻa Kiʻekiʻe

Mea hoʻopaʻa kūpono no ka granulation pulu ma nā ʻano haʻahaʻa (2-5%)
Hana i nā papa me ka paʻakikī kiʻekiʻe a me ka friability haʻahaʻa
Kāohi i ka capping, ʻoiai i nā ʻano hana lāʻau kiʻekiʻe

3. Hana like ʻole

Mea hoʻomānoanoa/mea hoʻopaʻano nā hopena ophthalmic a me nā waimaka hana
Mea hoʻohuihuino nā emulsions a me nā ʻano hana topical
Mea kumuno nā ʻāpana gel a me nā ʻōnaehana hoʻouna transdermal
Matrix muano nā ʻano lāʻau waha hoʻokuʻu mau ʻia
Polymer hoʻonui i ka solubilityno nā hoʻopuehu paʻa amorphous (i hiki ke hoʻāla ʻia e nā ʻenehana hana holomua)

4. Nā Waiwai Kino Kiʻekiʻe Loa

ʻO ka polymer non-ionic me ka solubility pH-independent - hōʻoia i ka hana mau ma waena o ka ʻōpū gastrointestinal
Paʻa kemika a ʻaʻohe ʻawahia
ʻO ka viscosity haʻahaʻa e hiki ai i ka ʻike paʻa kiʻekiʻe i loko o nā suspensions coating a me nā wai granulation, e hoʻomaikaʻi ana i ka pono hana
ʻAʻohe peroxides - kūpono no nā API koʻikoʻi