ʻO Croscarmellose Sodium Superdisintegrant no nā Papa Lāʻau Lapaʻau | Pehu wikiwiki, Pae Hoʻohana Haʻahaʻa 0.5-5% | Hoʻokō ʻia e USP/EP/JP

ʻO kā mākou Croscarmellose Sodium kahi superdisintegrant maʻemaʻe kiʻekiʻe i hoʻolālā ʻia no nā ʻano dosage paʻa waha e like me nā papa, nā capsules, a me nā granules. He sodium carboxymethylcellulose i hoʻopili ʻia i loko e hiki ʻole ke hoʻoheheʻe ʻia i ka wai akā pehu koke i 4-8 mau manawa o kona nui mua ma ka hoʻopili ʻana me nā media wai.Hāʻawi kēia ʻano fibrous kū hoʻokahi i ka hiki ke hoʻoheheʻe wai maikaʻi loa a me ka hana capillary, e hopena ana i ka disintegration papa maikaʻi loa a me ka hoʻonui ʻana i ka hoʻoheheʻe ʻana o ka lāʻau lapaʻau.Kūlike me nā lāʻau lapaʻau USP-NF, EP, JP, a me ChP me ka hoʻopaʻa inoa CDE F20209990136Pae hoʻohana maʻamau: 0.5-5.0% w/w (2% no ke kaomi pololei, 3% no ka granulation pulu)Kūpono no ka hoʻopili pololei ʻana, ka granulation pulu (intra- a i ʻole extra-granular), ka hoʻopili ʻana o ka wili, a me nā ʻano capsule

Kāhea iā mā˚ou

Nā kikoʻī huahana

Papa lāʻau lapaʻau Croscarmellose Sodium (CCS)

ʻIke Huahana

ʻO Croscarmellose Sodium kahi sodium carboxymethylcellulose i hoʻopili ʻia i loko, i hana kūikawā ʻia no ka hoʻohana ʻana ma ke ʻano he superdisintegrant i nā ʻano lāʻau lapaʻau.ʻAʻole e like me nā mea hoʻoheheʻe maʻamau, hāʻawi ia i nā waiwai hoʻoheheʻe kūikawā ma nā ʻano haʻahaʻa, e hōʻoiaʻiʻo ana i ka haki wikiwiki ʻana o nā papa a me ka hoʻonui ʻana i ka hoʻoheheʻe ʻana o ka lāʻau no ka hoʻomaikaʻi ʻana i ka bioavailability..

ʻIke Huahana:

Inoa Kemika:ʻO ka paʻakai Croscarmellose
Helu CAS:74811-65-7
Helu Hoʻopaʻa Inoa CDE:F20209990136
Hoʻokō ʻana i ka Pharmacopoeia:ChP, USP-NF, EP, JP, BP
Helu EC:629-739-2
Nā huaʻōlelo like:ʻO Carboxymethylcellulose i hoʻopili ʻia me ke keʻa Sodium, CCNa, Sodium Croscarmellose, E468

Nā Hiʻohiʻona Koʻikoʻi a me nā Pōmaikaʻi

1. ʻAno Hoʻopau Kiʻekiʻe Loa

Ka hoʻokaʻawale ʻana o ka hana pālua:Hoʻohui i ka hana capillary (wicking) me ka pehu wikiwiki
Pehu i4-8 manawa o kona nui muai ka wā e pili ai me ka wai
Hāʻawi ka ʻano fibrous i nā hiki ke omo wai maikaʻi loa
Hoʻokumu i ka hoʻonui mechanical e wāwahi koke i nā papa

2. Pae Hoʻohana Haʻahaʻa - Kūlana Kiʻekiʻe

Loaʻa ka hopena ma nā ʻano haʻahaʻa e like me0.5-5.0% w/w
Hoʻohana maʻamau: 2% no ke kaomi pololei, 3% no ka granulation pulu
Hoʻonā kūpono no ka hoʻomohala ʻana i ka hoʻohuihui ʻana

3. Ka maʻalahi o ka hoʻolālā ʻana

Kūpono no nā kaʻina hana papa āpau: hoʻopili pololei, granulation pulu, compaction roller
I ka granulation pulu, hiki ke hoʻohana ʻia intra-granularly, extra-granularly, a i ʻole i māhele ʻia ma waena o nā pae ʻelua
Hoʻohālikelike ʻia me nā ʻano capsule (10-25% hoʻohana)

4. Nā Waiwai Kino Maikaʻi Loa