Ka Laina Granulation ʻAno Pulu Kiʻekiʻe

He kūpono ia no ka hana ʻana i nā lāʻau paʻa ʻawahia loa, hana nui, a me nā lāʻau paʻa allergenic kiʻekiʻe, a pono e hōʻea i ka hoʻopaʻa ʻana OEB4 & OEB5 e hōʻemi i nā pōʻino o nā mea hana i ka wā o ke kaʻina hana a me ka hopena ma ke kaiapuni.

Ua kūlike nā lako me ka mana 2010 o Kina o GMP, European GMP, a me nā lula FDA, a ua hoʻokō i nā koi airtight o OEB, i mea e hōʻemi ai i ka hōʻino ʻana o ka huahana i nā pilina lako;

Nā Kūlana Kuhikuhi EHS no ka ʻOihana Lāʻau Lapaʻau Kina (2020); Nā Palena Hōʻike Hana no nā Kumu Pōʻino ma kahi Hana

E kiʻi i kahi ʻōlelo kūʻai

nā kikoʻī huahana

Laina Granulation ʻAno Pulu Kiʻekiʻe no ka Hoʻopaʻa ʻana

Nā hiʻohiʻona

1. E hoʻopaʻa i ka sila ʻeke ea, ka mana palekana interlock;

2. E hoʻohana i ka ʻeke PE a i ʻole ka valve ab no ka hoʻouka ʻana a me ka wehe ʻana;

3. E hoʻohana i ka ʻōnaehana BIBO no ka hoʻopau ʻana o ka ea, me nā kānana F9/H13;

4. Hoʻomaʻemaʻe WIP/Hoʻomaʻemaʻe CIP/Hoʻomaʻemaʻe wehe lima.

Ka wehewehe ʻana o ka hoʻopaʻa ʻana o OEB

ʻO nā API me ka cytotoxicity a me ka hana kiʻekiʻe he papa o nā mea hana lāʻau lapaʻau me ka hana pharmacological kiʻekiʻe, me ka dosage lapaʻau haʻahaʻa a me nā hopena ʻaoʻao liʻiliʻi, a ua huki nui ʻia ka manaʻo mai ka mākeke i nā makahiki i hala iho nei. ʻOiai he ākea ka mākeke no nā lāʻau lapaʻau ikaika loa, ke kū nei hoʻi lākou i nā pilikia nui aʻe. Ma waho aʻe o ka pepehi ʻana i nā cell cancer, hiki i nā lāʻau anti-tumor ke pepehi i nā cell maʻamau. Hiki i ko lākou sensitization ke hoʻoulu i nā hopena allergic i nā kānaka, a he mea ʻino loa ia i ke olakino o ka poʻe olakino. No laila, ʻo ka pilikia nui i manaʻo ʻia i ke kaʻina hana o nā API cytotoxic a me ka hana nui, ʻo ia ka ʻike ʻana i ka lepo. ʻO ka hopena maikaʻi loa ka hoʻohana ʻana i ka ʻenehana hoʻokaʻawale airtight e kāohi i ka nui o ka leakage lepo i ke kaʻina hana. Ma muli o kēia ʻano, ke aʻo nui nei kēia papahana i nā waiwai OEL (Occupational Exposure Limit) e pili ana ma lalo o nā pae pilikia toxicity mea hana like ʻole, a me nā lako like ʻole OEB airtight level a me ka hoʻolālā airtight. Wahi a nā ʻano o nā mea maka cytotoxic a me ka hana nui, ma muli o ka ʻenehana sila labyrinth e kū nei, ʻenehana sila kaomi maikaʻi ʻole a me ka ʻenehana hoʻokaʻawale airtight, ua aʻo ʻia nā ʻano hui sila like ʻole no ia mau mea. Hiki i ka ʻenehana sila micro-leakage ke ālai a ālai paha me ka cytotoxicity kiʻekiʻe. Nā kahawai leakage o nā API hana e kāohi i ka helu leakage

Nā koi lako OEB

1. Pono ʻo OEB 1~2 e hoʻonohonoho i nā hale hana hoʻoulu makani kūloko, e like me ka hoʻoulu ʻana i ka ea kūloko ma nā wahi i hōʻike ʻia.

2. OEB 3 Ke pili ka pilina hana, pono e hoʻohana ʻia nā lako a me nā pono ea ea e like me ka hiki, a me nā hana kaohi e like me ka hoʻoulu ʻana i ka ea, ka uhi kahe laminar, kahi hana kūʻokoʻa me ka mea hoʻoulu ea kūloko, ka uhi uahi, a pēlā aku e hoʻohana ʻia ma nā ʻāpana i hōʻike ʻia o ka lepo lāʻau.

3. Pae OEB 4-5 Pono e hāʻawi ʻia ka mea nui i ka hoʻohana ʻana i nā lako a me nā pono hana piha piha, a me ka hoʻolālā ʻana i nā ala hana ʻenehana i hoʻopaʻa ʻia. Pono ka laina huahana e hoʻohana i nā lako a me nā pono hana i hoʻopaʻa ʻia. E pili ana i ka pilina hana, nā hana hoʻomalu e like me ka isolator, ka hana pani pahu mīkina lima, ka valve α-β, ka ʻeke i loko a me ka ʻeke i waho, a pēlā aku. Pono nā lako hana e hoʻohana i kona ea ponoʻī, e like me ka mea hoʻomaloʻo ʻekolu-i-hoʻokahi.